Febrile non-hemolytic transfusion reaction

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Febrile non-hemolytic transfusion reaction
Classification and external resources
ICD-10 Y44.6, Y44.7

Febrile non-hemolytic transfusion reaction is a type of transfusion reaction that is associated with fever but not directly with hemolysis. Most commonly caused by antibodies directed against donor leukocytes and HLA antigens.

It is abbreviated "FNHTR".[1]

The reaction can be mediated by cytokines.[2][3]

Acetaminophen and diphenhydramine have been used in treatment, and leukoreduction of future transfusions is sometimes performed.[4]

References[edit]