Winiwarter is credited for providing an early description of thromboangiitis obliterans. In 1879 he described a situation involving a 57-year old male patient who had an unusual obliteration of the arteries and veins of the leg. He attributed this disorder to new growth of tissue from the intima, and proposed the name "endarteritis obliterans" for the disease. Winiwarter's discovery wasn't the first modern description of the condition, as three years earlier, bacteriologistCarl Friedländer (1847–1887) referred to it as "arteritis obliterans". In 1908, American surgeonLeo Buerger (1879–1943) further described the disease, and in 1924 published a monograph based on analyses taken from 500 patients. The disease was later referred to as "Winiwarter–Buerger syndrome", "Buerger's disease" or as "thromboangiitis obliterans".