Fenamic acid

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Fenamic acid
Fenamic acid.png
Identifiers
CAS number 91-40-7 YesY
PubChem 4386
ChEBI CHEBI:34756 N
ChEMBL CHEMBL23832 N
Jmol-3D images Image 1
Properties
Molecular formula C13H11NO2
Molar mass 213.23 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Fenamic acid is a molecule which serves as a parent structure for several non-steroidal anti-inflammatory drugs, including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid.

This compound may be synthesized by the reaction of 2-chlorobenzoic acid and aniline, with base and copper oxide catalyst in the Goldberg reaction.[1]

GoldmanReaction.svg

The self-condensation of fenamic acid yields acridone.[1]

References[edit]

  1. ^ a b C. F. H. Allen and G. H. W. McKee (1943), "Acridone", Org. Synth. ; Coll. Vol. 2: 15