Fenoprofen

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Fenoprofen
Fenoprofen2DACS.svg
Systematic (IUPAC) name
2-(3-phenoxyphenyl)propanoic acid
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a681026
Pregnancy cat. D (US) C
Legal status POM (UK) -only (US)
Routes Oral
Pharmacokinetic data
Metabolism Major urinary metabolites are fenoprofen glucuronide and 4′-hydroxyfenoprofen glucuronide.
Half-life 3 hours
Excretion Renal (~90%)
Identifiers
CAS number 29679-58-1 YesY
ATC code M01AE04
PubChem CID 3342
DrugBank DB00573
ChemSpider 3225 YesY
UNII RA33EAC7KY YesY
KEGG D02350 YesY
ChEBI CHEBI:5004 YesY
ChEMBL CHEMBL1297 YesY
Chemical data
Formula C15H14O3 
Mol. mass 242.26986 g/mol
 YesY (what is this?)  (verify)

Fenoprofen is a non-steroidal anti-inflammatory drug. Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain. Fenoprofen is marketed in the USA as Nalfon.

Pharmacology[edit]

Decreases inflammation, pain, and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis.

Contraindications[edit]

History of significantly impaired renal function; patients with known hypersensitivity to any component of the product; patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs; treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.

Drug interactions[edit]

Laboratory test interactions[edit]

False elevation in free and total serum T 3 as measured by Amerlex-M kit.

Brand names[edit]

References[edit]