Murad at a lecture in 2008
September 14, 1936 |
|Institutions||University of Virginia (1970-81), Stanford (1981-88), Abbott Laboratories (1988-93), University of Texas Medical School at Houston (1997-2011), George Washington University (2011-Present)|
|Alma mater||DePauw University (BS, 1958) and Case Western Reserve University (MD-Ph.D., 1965)|
|Doctoral advisor||Earl Sutherland, Jr. and Theodore Rall|
|Known for||Discoveries concerning cyclic GMP as a signaling molecule in the cardiovascular system|
|Notable awards||Nobel Prize in Physiology or Medicine (1998) and the Albert Lasker Award for Basic Medical Research (1996)|
Ferid Murad (born September 14, 1936) is a physician and pharmacologist, and a co-winner of the 1998 Nobel Prize in Physiology or Medicine. He is also an honorary member of the Academy of Sciences and Arts of Kosovo.
He was born in Whiting, Indiana to Jabir Murat Ejupi, an Albanian immigrant from Llakavica-Gostivar, Macedonia, and Henrietta Bowman, an American Christian, Ferid Murad was raised as a Christian. He received his undergraduate degree in chemistry from the pre-med program at DePauw University in 1958, and MD and pharmacology Ph.D. degrees from Case Western Reserve University in 1965. He was an early graduate of the first explicit MD/PhD program which would later lead to the development of the prestigious Medical Scientist Training Program. He then joined the University of Virginia, where he was made professor in 1970, before moving to Stanford in 1981. Murad left his tenure at Stanford in 1988 for a position at Abbott Laboratories, where he served as a vice president until starting his own biotechnology company, the Molecular Geriatrics Corporation, in 1993. The company experienced financial difficulties, and in 1997 Murad joined the University of Texas Medical School at Houston to create a new department of integrative biology, pharmacology, and physiology. There, he was the chairman of Integrative Biology and Pharmacology, Professor and Director Emeritus of The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Disease, John S. Dunn Distinguished Chair in Physiology and Medicine, Deputy director of The Brown Foundation Institute of Molecular Medicine, and later a Professor at the Brown Foundation Institute of Molecular Medicine. In April 2011, he moved to the George Washington University as a Professor in the Department of Biochemistry and Molecular Biology.
Murad's key research demonstrated that nitroglycerin and related drugs worked by releasing nitric oxide into the body, which relaxed smooth muscle by elevating intracellular cyclic GMP. The missing steps in the signaling process were filled in by Robert F. Furchgott and Louis J. Ignarro of UCLA, for which the three shared the 1998 Nobel Prize (and for which Murad and Furchgott received the Albert Lasker Award for Basic Medical Research in 1996). There was some criticism, however, of the Nobel committee's decision not to award the prize to Salvador Moncada, who had independently reached the same results as Ignarro.
- "Academy of Sciences and Arts of Kosovo". Academy of Sciences and Arts of Kosovo. Retrieved 4 May 2010.
- “Ferid Murad autobiography”, Nobel Foundation
- Nobel Laureate to Join GW | Learninig & Search – the George Washington University]
- Arritjet ia dedikoj kombit tim!, Telefrafi, 2012-05-31 (in Albanian). As noted in the "Talk" section of this Wikipedia article, however, Murad appears to have referred to the land of his birth, education, and residence, the United States of America (and not the land of his father's birth, Albania), as "[his] nation".