Filaminast

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Filaminast
Filaminast.png
Systematic (IUPAC) name
[1-(3-cyclopentyloxy-4-methoxyphenyl)ethylideneamino] carbamate
Clinical data
Legal status ?
Identifiers
CAS number 141184-34-1
ATC code None
PubChem CID 9578243
DrugBank DB02660
ChemSpider 7852607
UNII CDD69JC61J YesY
KEGG D04185
Chemical data
Formula C15H20N2O4 
Mol. mass 292.33 g/mol

Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). As such, its primary indication is in the therapeutic treatment of asthma and chronic obstructive pulmonary disease (COPD).[1]

Synthesis[edit]

Filaminast synth.png[2]

References[edit]

  1. ^ Giembycz, M A (2008). "Can the anti-inflammatory potential of PDE4 inhibitors be realized: guarded optimism or wishful thinking?". British Journal of Pharmacology 155 (3): 288–90. doi:10.1038/bjp.2008.297. PMC 2567889. PMID 18660832. 
  2. ^ Lombardo, L. J.; U.S. Patent 5,124,455 (1992).