File:Paracetamol metabolism.svg

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Description	English: Simplified schematic of the key pathways of paracetamol metabolism in the human body. The first step in conversion of paracetamol to NAPQI has been omitted for clarity. Set in Myriad Pro. Legend    Pathways to non-toxic metabolites    Pathway to toxic metabolites (CYP-mediated)    Detoxification pathway Abbreviations GlcA, glucuronic acid; GSH, glutathione; NAPQI, N-acetyl-p-benzoquinone imine. Português: Esquema simplificado das principais vias de biotransformação do paracetamol em humanos. Para maior clareza, omitiu-se a primeira etapa da conversão do paracetamol à N-acetil-benzoquinoneimina. Diagrama composto em Myriad Pro. Legenda    Vias de conversão a metabólitos atóxicos    Via de conversão a metabólitos tóxicos (mediada pelo sistema P450)    Via de detoxificação Abreviações GlcA, ácido glicurônico; GSH, glutationa; NAPQI, N-acetil-benzoquinoneimina. This vector image was created with Inkscape.
Date	18 January 2009(2009-01-18)
Source	Own work, after Henry, John (1995). “Poisoning”, in Marshall, William Leonard. Clinical biochemistry: metabolic and clinical aspects, p. 666, Edinburgh: Churchill Livingstone, ISBN 9780443043413; and Hendrickson, Robert G.; Kenneth E. Bizovi (2006). “Acetaminophen”, in Nelson, Lewis H.; Flomenbaum, Neal; Goldfrank, Lewis R. et al. Goldfrank's toxicologic emergencies, p. 525, New York: McGraw-Hill, ISBN 9780071437639. Both retrieved on January 18, 2009 through Google Book Search.
Author	Fvasconcellos (talk · contribs)
Permission (Reusing this file)	Public domainPublic domainfalsefalse I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law. Public domainPublic domainfalsefalse
Other versions	File:Paracetamol metabolism.png (English, also simpified) File:Métabolisme paracetamol.png (French, also simplified) File:Metabolizm paracetamolu.svg (more detailed, Polish)

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	13:13, 19 January 2009		385 × 385 (185 KB)	Fvasconcellos	fixed NAPQI structure
	17:47, 18 January 2009		385 × 385 (185 KB)	Fvasconcellos	alignment
	16:15, 18 January 2009		385 × 385 (191 KB)	Fvasconcellos	== Summary == {{validSVG}} {{Information |Description= {{en|Simplified schematic of the key pathways of {{w|paracetamol}} metabolism in the human body. The first step in conversion of paracetamol to NAPQI has been omitted for clari

• Paracetamol
• Paracetamol toxicity
• User:Gregchristie1982/Sandbox

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