Flaviviridae

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Flaviviruses
West Nile virus
Virus classification
Group: Group IV ((+)ssRNA)
Order: Unassigned
Family: Flaviviridae
Genera

The Flaviviridae are a family of viruses that are primarily spread through arthropod vectors (mainly ticks and mosquitoes). The family gets its name from Yellow Fever virus, a type virus of Flaviviridae; flavus means yellow in Latin. (Yellow fever in turn was named because of its propensity to cause jaundice in victims.)[1]

Flaviviridae have monopartite, linear, single-stranded RNA genomes of positive polarity, 9.6 to 12.3 kilobase in length. The 5'-termini of flaviviruses carry a methylated nucleotide cap, while other members of this family are uncapped and encode an internal ribosome entry site. Virus particles are enveloped and spherical, about 40–60 nm in diameter.

Taxonomy[edit]

This family includes the following genera:

Clinical importance[edit]

Major diseases caused by the Flaviviridae family include:

References[edit]

  1. ^ "Flaviviridae". Microbe Wiki. Retrieved July 22, 2008. 
  2. ^ Paula T, Pablo R, Eugenia V, Pablo B, Sabino P, José M et al. (2009). "New drug targets for hepatitis C and other Flaviviridae viruses". Infect Disord Drug Targets 9 (2): 133–47. doi:10.2174/187152609787847749. PMID 19275702. 

External links[edit]