Flavokavain A

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Flavokavain A
Flavokavain A.svg
Identifiers
CAS number 37951-13-6 YesY
PubChem 5355469
2224776
Jmol-3D images Image 1
Properties
Molecular formula C18H18O5
Molar mass 314.33 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references

Flavokavain A is a flavokavain found in the kava plant.[1] It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway.[2]

See also[edit]

References[edit]

  1. ^ Dharmaratne, H. Ranjith W.; N. P. Dhammika Nanayakkara; Ikhlas A. Khan (February 2002). "Kavalactones from Piper methysticum, and their 13C NMR spectroscopic analyses". Phytochemistry 59 (4): 429–33. doi:10.1016/S0031-9422(01)00443-5. PMID 11830162. 
  2. ^ Zi X, Simoneau AR (April 2005). "Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.". Cancer Research 65 (8): 3479–86. doi:10.1158/0008-5472.CAN-04-3803. PMID 15833884. 

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