Flavoxate

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Flavoxate
Flavoxate.svg
Systematic (IUPAC) name
2-(1-piperidyl)ethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate
Clinical data
AHFS/Drugs.com monograph
MedlinePlus a682706
Legal status ?
Identifiers
CAS number 15301-69-6 YesY
ATC code G04BD02
PubChem CID 3354
DrugBank DB01148
ChemSpider 3237 YesY
UNII 3E74Y80MEY YesY
KEGG D07961 YesY
ChEBI CHEBI:5088 YesY
ChEMBL CHEMBL1493 N
Chemical data
Formula C24H25NO4 
Mol. mass 391.46 g/mol
 N (what is this?)  (verify)

Flavoxate is an anticholinergic with antimuscarinic effects. Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by antagonizing muscarinic receptors.

Clinical uses[edit]

Flavoxate is used to treat urinary bladder spasms. It is available under the trade name Urispas (Paladin),Genurin (by Recordati, Italy) in Italy and KSA,Uritac by El Saad company in Syria, under the name Bladderon by Nippon Shinyaku of Japan, or Bladuril in Chile.

Flavoxate is indicated for symptomatic relief of interstitial cystitis, dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.

Side effects[edit]

Flavoxate is generally well tolerated, but can potentially cause, vomiting, upset stomach, dry mouth or throat, blurred vision, eye pain,[1] and increased sensitivity of your eyes to light.

Contraindications[edit]

Flavoxate is contraindicated in patients who have any of the following obstructive conditions: pyloric or duodenal obstruction, obstructive intestinal lesions or ileus, achalasia, gastrointestinal hemorrhage and obstructive uropathies of the lower urinary tract.

Notes[edit]

  1. ^ Zakir SM, Zaka-ur-Rab S, Salman MT, Khan RA. Bilateral acute angle closure glaucoma in a 50 year old female after oral administration of flavoxate. British Journal of Clinical Pharmacology. 2008. 66(5):726-727

References[edit]