It ran 16 issues from June 1999 until January 2001 and featured the talents of Jim Lee, Bill Willingham, Frank Quitely and many others. Rumors of being canceled seemed to plague the book throughout its printing. 
Tim Truman said of the series: "...the best art I've done in any single comics story is on the "Brer Hoodoo" short story I did with Joe for Vertigo's Flinch anthology." Issue #11 won a Horror Writers' Association Bram Stoker Award for "Red Romance" by Joe R. Lansdale.
Issue #11 also received a nomination for a 2001 Will Eisner Comic Industry award for best cover artist (Phil Hale).
- Flinch at the Comic Book DB