SR 200 is signed from Hernando through Apache Shores and Stokes Ferry in Citrus County through Marion Oaks to Ocala in Marion County, where it becomes an unsigned route for US 301 north to Callahan. Then it is signed again from Callahan to Fernandina Beach, signed concurrently with SR A1A.
State Road 200A (SR 200A) in Ocala and northern Marion County is now County Road 200A. It was also former U.S. Route 301 Alternate. The first segment is named 20th Street and begins at US 301 in Ocala north of a railroad bridge. Upon reaching Northeast Eighth Road, former SR 200 becomes Jacksonville Road, a street name it carries until it terminates with US 301 in Citra. Other County Road 200A's can be found in Alachua, Bradford, and Nassau Counties.
County Road 200A is one of two suffixed alternates of State Road 200 in Lawtey. It runs along the west side of US 301/SR 200 from the aforementioned route through CR 225 (Madison Street). One block later the route turns right onto Lake Street and runs for three blocks until it terminates at the north end of a multiplex with US 301 and CR 225.
County Road 200B is another one of the two suffixed alternates of State Road 200 in Lawtey. It runs along the east side of US 301/SR 200 and begins at the same route just north of the southern terminus of CR 200A. CR 200B runs east to cross the CSX Wildwood Subdivision, then winds around local streets within Lawtey until it terminates at CR 225(Lake Street).
County Road 200A is the last suffixed alternate of SR 200 in the state. It runs along Pages Dairy Road west of US 17 in Yulee and runs north of the road until it reaches Chester River Road(a.k.a.; Old Chester Road) in Lofton, then turns south along Chester River Road until it terminates at SR 200, which at this point is also multplexed with SR A1A.