Florida wine refers to wine made from grapes and other tropical fruit grown in the U.S. state of Florida. Wine grapes were grown in Florida earlier than anywhere else in the United States. The first wine grapes were planted in the 16th century by Spanishmissionaries for the production of sacramental wine for Christianreligious ceremonies. Because of the tropical climate and grapevinediseases, particularly Pierce's disease, vitis vinifera does not grow well in Florida. In the 1930s, researchers at the University of Florida helped develop new hybrid grape varieties specifically suited for Florida's climate, including Stover, Blanc Du Bois, Swanee and Miss Blanc. As early as 1991 Florida Orange Groves Winery began to develop wines made from 100% tropical fruit. Thanks to their efforts the term Florida Wine now encompasses varieties like mango, key lime, orange, grapefruit, blueberry and strawberry. Following in the footsteps of Florida Orange Groves Winery are several other wineries located in Florida now experimenting with tropical fruits. There are no designated American Viticultural Areas in Florida.