Flosequinan

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Flosequinan
Flosequinan.svg
Systematic (IUPAC) name
(RS)-7-fluoro-3-methanesulfinyl-1-methyl-1,4-dihydroquinolin-4-one
Clinical data
Legal status
?
Identifiers
CAS number 76568-02-0
ATC code C01DB01
PubChem CID 4474062
ChemSpider 3672315
UNII 6NB119DLU7 YesY
KEGG D04195 YesY
Chemical data
Formula C11H10FNO2S 
Mol. mass 239.267 g/mol
 YesY (what is this?)  (verify)

Flosequinan is a quinolone vasodilator. It has direct relaxing effects on peripheral arteries and veins. It is administered orally in cases of congestive heart failure in patients who are not responsive to digitalis or ACE inhibitors. It was sold under the trade name Manoplax.

It was withdrawn from the US market in October 1993 due to an increased risk of hospitalization or death.[1]

References[edit]

  1. ^ "Heart drug withdrawn - Boots Pharmaceuticals' Manoplax". FDA Consumer. 1993. Retrieved 2008-12-01.