Fludroxycortide

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Fludroxycortide
Fludroxycortide.svg
Systematic (IUPAC) name
6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione
Clinical data
Trade names Cordran, Haelan
AHFS/Drugs.com Micromedex Detailed Consumer Information
Legal status
Routes Topical
Identifiers
CAS number 1524-88-5 YesY
ATC code D07AC07
PubChem CID 15209
DrugBank DB00846
ChemSpider 14475 YesY
UNII 8EUL29XUQT YesY
KEGG D00328 YesY
ChEMBL CHEMBL1201012 N
Chemical data
Formula C24H33FO6 
Mol. mass 436.514 g/mol
 N (what is this?)  (verify)

Fludroxycortide (INN, also known as flurandrenolone or flurandrenolide[1]) is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).[2][3]

Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.[4][5]

References[edit]

  1. ^ CID 15209 from PubChem
  2. ^ Drugs.com: Fludroxycortide
  3. ^ Patient.co.uk: Fludroxycortide
  4. ^ Haelan Tape Summary of Product Characteristics
  5. ^ Nakamura, H.; Motoyoshi, S.; Ishii, K.; Seto, Y.; Shimizu, M. (1980). "Anti-inflammatory activity of a topical glucocorticoid, fludroxycortide tape in experimental animals (author's transl)". Nihon yakurigaku zasshi. Folia pharmacologica Japonica 76 (7): 595–607. PMID 7215997.  edit