Fludroxycortide
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| Systematic (IUPAC) name | |
| 6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione | |
| Clinical data | |
| Trade names | Cordran, Haelan |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Pregnancy cat. | ? |
| Legal status | POM (UK) |
| Routes | Topical |
| Identifiers | |
| CAS number | 1524-88-5  |
| ATC code | D07AC07 |
| PubChem | CID 15209 |
| DrugBank | APRD00982 |
| ChemSpider | 14475 |
| UNII | 8EUL29XUQT |
| KEGG | D00328 |
| ChEMBL | CHEMBL1201012  |
| Chemical data | |
| Formula | C24H33FO6 |
| Mol. mass | 436.514 g/mol |
| SMILES | eMolecules & PubChem |
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Fludroxycortide (INN, also known as flurandrenolone or flurandrenolide[1]) is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).[2][3]
Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.[4][5]
[edit] References
- ^ CID 15209 from PubChem
- ^ Drugs.com: Fludroxycortide
- ^ Patient.co.uk: Fludroxycortide
- ^ Haelan Tape Summary of Product Characteristics
- ^ Nakamura, H.; Motoyoshi, S.; Ishii, K.; Seto, Y.; Shimizu, M. (1980). "Anti-inflammatory activity of a topical glucocorticoid, fludroxycortide tape in experimental animals (author's transl)". Nihon yakurigaku zasshi. Folia pharmacologica Japonica 76 (7): 595–607. PMID 7215997.
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