Compartment (pharmacokinetics)
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In pharmacokinetics, a compartment is a defined volume of body fluids. It is distinguished from anatomic compartments, which are bounded by fasciae. It is used in multi-compartment models.
Examples[edit]
There are five major body compartments:[1]
The transcellular compartment includes fluids in the pleural cavity or peritoneal cavity.
Comparison table[edit]
| Compartment | estimated % of body mass[2] |
|---|---|
| blood plasma | 5 |
| interstitial fluid | 16 |
| fat tissue | 20 (see also body fat percentage) |
| intracellular fluid | 35 |
| transcellular fluid | 2 |
Mnemonic: 60-40-20-15-5: % of TBW, Intracellular fluid, Extracellular fluid, interstitial fluid, plasma
References[edit]
- ^ Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 102
- ^ Unless else specified in table, then ref s: Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 102
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