Fluvastatin

Fluvastatin

Systematic (IUPAC) name
(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid
Clinical data
Trade names	Lescol
AHFS/Drugs.com	monograph
MedlinePlus	a694010
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Pharmacokinetic data
Protein binding	98%
Half-life	2.5 hours
Identifiers
CAS number	93957-54-1 Y
ATC code	C10AA04
PubChem	CID 446155
DrugBank	APRD00346
ChemSpider	393587 Y
UNII	4L066368AS Y
KEGG	D07983 Y
ChEBI	CHEBI:38565 Y
ChEMBL	CHEMBL1078 Y
Chemical data
Formula	C24H26FNO4
Mol. mass	411.466 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m1/s1 Y Key:FJLGEFLZQAZZCD-MCBHFWOFSA-N Y
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Fluvastatin (trade names Lescol, Canef, Vastin) is a member of the drug class of statins, used to treat hypercholesterolemia and to prevent cardiovascular disease.

It has also been shown to exhibit antiviral activity against Hepatitis C in a study with 31 patients. This effect has been described as modest, variable, and often short-lived by the authors.