Formyl-CoA transferase

Formyl-CoA transferase
Identifiers
EC number	2.8.3.16
CAS number	128826-27-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles

In enzymology, a formyl-CoA transferase (EC 2.8.3.16) is an enzyme that catalyzes the chemical reaction

formyl-CoA + oxalate $\rightleftharpoons$ formate + oxalyl-CoA

Thus, the two substrates of this enzyme are formyl-CoA and oxalate, whereas its two products are formate and oxalyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is formyl-CoA:oxalate CoA-transferase. Other names in common use include formyl-coenzyme A transferase, and formyl-CoA oxalate CoA-transferase.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1T3Z, 1T4C, 1VGQ, and 1VGR.

References

• Baetz AL, Allison MJ (1990). "Purification and characterization of formyl-coenzyme A transferase from Oxalobacter formigenes". J. Bacteriol. 172 (7): 3537–40. PMC 213325. PMID 2361939. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=213325. 
• Sidhu H, Ogden SD, Lung HY, Luttge BG, Baetz AL, Peck AB (1997). "DNA sequencing and expression of the formyl coenzyme A transferase gene, frc, from Oxalobacter formigenes". J. Bacteriol. 179 (10): 3378–81. PMC 179125. PMID 9150242. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=179125.