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Born in Rome, Italy, she is the daughter of former Bond girl, Barbara Bach and businessman Augusto Gregorini. Her mother is of Jewish and Irish descent. She is also the stepdaughter of Beatles drummer Ringo Starr. In 1990 she graduated from Brown University.
A Brown University graduate with a Theater Arts major, Francesca sold scripts to both HBO and Paramount before co-helming her directorial debut Tanner Hall, which was an official selection at the Toronto Film Festival (2009). Her latest film Emanuel and the Truth About Fishes (Starring Jessica Biel Kaya Scodelario Alfred Molina) was selected for the US Dramatic Competition at the Sundance Film Festival 2013.
Francesca and Tatiana von Furstenberg, co-wrote and co-directed the independent film Tanner Hall, a coming of age story set in an all-girls boarding school in Rhode Island, which is loosely based on their own experiences during adolescence. “Naturally there are some autobiographical elements, combined with things we'd witness in boarding school, and many other parts that we made up completely. You will certainly find characteristics of both of us in each of the 4 main girls and if you spend even a half hour with us, it will be very apparent to you, which girls are most like me and which ones are most like Tatiana”, said Gregorini in an interview.