Born in France in 1859 and educated at the Institut Catholique de Paris, Gigot was a student of the liberal Alfred Loisy. After ordination in 1884, Gigot emigrated to America and taught Scripture at St. John's Seminary, Brighton, Massachusetts (1885–1899), where he was mentor to the Paulist James Martin Gillis, then St. Mary's Seminary, Baltimore (1899–1905), then St. Joseph's Seminary, Dunwoodie (1905–1920), a Catholic theological school under the direction of Sulpicians, but publishing the modernist New York Review (till 1908). Gigot held revisionist views of Scripture and the Sulpician leadership in Paris wanted Father James Francis Driscoll to rein Gigot in. Driscoll and Gigot "chafed against the scholasticism which they refused to see as exhaustive of orthodoxy". Gigot and the others left the Sulpicians to join the Archdiocese of New York.
Gigot died at St. Vincent's Seminary,Pennsylvania in 1920.
- General introduction to the study of the Holy Scriptures. Abridged ed. By Rev. Francis E. Gigot New York Cincinnati [etc.] Benziger brothers. 1900, 1904.
- Michael J. DeVito The New York review, 1905-1908 1977 "Francis Ernest Charles Gigot (1859-1920) was another priest of exceptional talent associated with The Review. Born in France, he studied under the Christian Brothers and attended the University of France,"
- Martin E. Marty Modern American Religion, Volume 1: The Irony of It All, 1893-1919 1977, Page 199