Francis Thomas "Frank" Agnew (born August 18, 1964) is an American guitarist, best known for being a member of punk band The Adolescents.
Agnew joined The Adolescents in 1980 after leaving Social Distortion. He left when The Adolescents broke up in the summer of 1981, and joined the band Legal Weapon with Steve, and then played with T.S.O.L. Like the rest of the original line-up, Frank returned to The Adolescents in 1986, but soon left along with Casey Royer. The Adolescents reformed in 1988 to release Balboa Fun*Zone and Frank played guitar on two of the tracks, however, he did not rejoin the new band line-up. This version of the Adolescents broke up in 1989. He was part of the 2004 reformed Adolescents and was sole guitarist on the 2005 "O.C. Confidential" album. He is the brother of guitarist Rikk Agnew.