Chin is considered to be one of the pioneers in Asian American theatre. He founded the Asian American Theatre Workshop, which became the Asian American Theater Company in 1973. He first gained notoriety as a playwright in the 1970s. His play The Chickencoop Chinaman was the first by an Asian American to be produced on a major New York stage. Stereotypes of Asian Americans, and traditional Chinese folklore are common themes in much of his work. Frank Chin has accused other Asian American writers, particularly Maxine Hong Kingston, of furthering such stereotypes and misrepresenting the traditional stories. Chin, during his professional career, has been highly critical of American writer, Amy Tan, for her telling of Chinese-American stories, indicating that her body of work has furthered and reinforced stereotypical views of this group. On a radio program, Chin has also debated the scholar Yunte Huang regarding the latter's evaluation of Charlie Chan in his writing. This discussion was later evaluated on the activist blog "Big WOWO."
In addition to his work as an author and playwright, Frank Chin has also worked extensively with Japanese American resisters of the draft in WWII. His novel, Born in the U.S.A., is dedicated to this subject.