Günter Blobel at MPI-CBG symposium, November 2008
21 May 1936 |
|Citizenship||German and American|
|Alma mater||University of Tübingen
University of Wisconsin-Madison
|Academic advisors||George Palade|
|Doctoral students||Vishwanath R. Lingappa, Larry Gerace, Mike McCune, Keith Mostov, Anton Titov, Monique Floer, Peter Walter, Johanna Napetschnig, Kuo-Chiang Hsia, Vivien Nagy, Martin Kampmann|
|Other notable students||David J. Anderson|
|Known for||Protein targeting|
|Notable awards||Nobel Prize in Physiology or Medicine (1999)|
Günter Blobel (born May 21, 1936) is a German American biologist and 1999 Nobel Prize laureate in Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell.
Günter Blobel was born in Waltersdorf in the Prussian Province of Lower Silesia. In January 1945 his family fled from native Silesia from the advancing Red Army. On their way to the West they passed through the beautiful old city of Dresden, which left deep impressions in the young boy. Only days after their stay in Dresden it was destroyed in the catastrophic air bombing between 13 February and 15 February 1945. The family could witness this event some 30 kilometers away and the young boy again was deeply impressed by the red night sky reflecting the firestorm in the burning city, but the war was still not at its end and Blobel's 19-year-old sister was killed some weeks later in an air attack on a train she was travelling in, and buried in a mass grave.
After the war Günter Blobel grew up and attended gymnasium in the Saxon town of Freiberg. He graduated at the University of Tübingen in 1960 and received his Ph.D. from the University of Wisconsin–Madison in 1967. He was appointed to the Howard Hughes Medical Institute in 1986.
Blobel was awarded the 1999 Nobel Prize in Physiology or Medicine for the discovery of signal peptides. Signal peptides form an integral part of protein targeting, a mechanism for cells to direct newly synthesized protein molecules to their proper location by means of an "address tag" (i.e. a signal peptide) within the molecule.
Blobel is also well known for his direct and active support for the rebuilding of Dresden in Germany, becoming, in 1994, the founder and president of the nonprofit "Friends of Dresden, Inc." He donated all of the Nobel award money to the restoration of Dresden, in particular for the rebuilding of the Frauenkirche (completed in 2005) and the building of a new synagogue. In Leipzig he pursued a rebuilding of the Paulinerkirche which had been blown up by the communist regime of East Germany in 1968, arguing: "This is much more than a church — this is a shrine of German cultural history, connected to the most important names in German cultural history."
Blobel has worked at the Rockefeller University in New York City since 1968. He lives in Manhattan's Upper East Side with his wife and three English setter dogs. He is also on the board of directors for Nestlé and the Board of Scientific Governors at The Scripps Research Institute. Furthermore, he is also Co-Founder and Chairman of the Scientific Advisory Board for Chromocell Corporation. He also sits on the Selection Committee for Life Science and Medicine which chooses winners of the Shaw Prize.
- 1978: National Academy of Sciences, Steel Foundation Award in Molecular Biology
- 1982: Gairdner Foundation International Award
- 1987: Louisa Gross Horwitz Prize from Columbia University
- 1993: Albert Lasker Award for Basic Medical Research
- 1995: Ciba Drew Award in Biomedical Research
- 1996: King Faisal Award
- 1997: Mayor's Award for Excellence in Science and Technology
- 1999: Massry Prize from the Keck School of Medicine, University of Southern California
- 1999: Nobel Prize in Physiology or Medicine
- 2001: Pontifical Academy of Sciences
- "You are one and they are many. You have to work day and night, or you will be crushed like a roach"
- The Nobel Prize in Physiology or Medicine 1999 / Günter Blobel nobelprize.org
- Perils of Paulinerkirche / Leipzig Debates Bid to Rebuild Church Razed by Communists National Public Radio 22 June 2003
- Gunter Blobel, M.D., Ph.D. / Chairman of the Scientific Advisory Board
- D.J. Anderson, verbatim recollection, Blobel laboratory early 1980s
- Blobel's page at Rockefeller University
- Blobel's Nobel Prize autobiography
- Freeview video 'An Interview with Günter Blobel' by the Vega Science Trust
- Official site of the Louisa Gross Horwitz Prize
- Information about Blobel as Distinguished German-American of the Year 2005 (German-American Heritage Foundation)