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Polypeptide N-acetylgalactosaminyltransferase 13
Symbols GALNT13 ; GalNAc-T13; H_NH0187G20.1; WUGSC:H_NH0187G20.1
External IDs OMIM608369 MGI2139447 HomoloGene62167 GeneCards: GALNT13 Gene
EC number
Species Human Mouse
Entrez 114805 271786
Ensembl ENSG00000144278 ENSMUSG00000060988
UniProt Q8IUC8 Q8CF93
RefSeq (mRNA) NM_052917 NM_173030
RefSeq (protein) NP_443149 NP_766618
Location (UCSC) Chr 2:
154.73 – 155.31 Mb
Chr 2:
54.44 – 55.12 Mb
PubMed search [1] [2]

Polypeptide N-acetylgalactosaminyltransferase 13 is an enzyme that in humans is encoded by the GALNT13 gene.[1][2][3]

The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM][3]


  1. ^ Nagase T, Kikuno R, Ohara O (Sep 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Res 8 (4): 179–87. doi:10.1093/dnares/8.4.179. PMID 11572484. 
  2. ^ Zhang Y, Iwasaki H, Wang H, Kudo T, Kalka TB, Hennet T, Kubota T, Cheng L, Inaba N, Gotoh M, Togayachi A, Guo J, Hisatomi H, Nakajima K, Nishihara S, Nakamura M, Marth JD, Narimatsu H (Dec 2002). "Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen". J Biol Chem 278 (1): 573–84. doi:10.1074/jbc.M203094200. PMID 12407114. 
  3. ^ a b "Entrez Gene: GALNT13 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)". 

Further reading[edit]