GANAB

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Glucosidase, alpha; neutral AB
Identifiers
Symbols GANAB ; G2AN; GLUII
External IDs OMIM104160 MGI1097667 HomoloGene5426 ChEMBL: 2519 GeneCards: GANAB Gene
EC number 3.2.1.84
RNA expression pattern
PBB GE GANAB 211934 x at tn.png
PBB GE GANAB 214626 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23193 14376
Ensembl ENSG00000089597 ENSMUSG00000071650
UniProt Q14697 Q8BHN3
RefSeq (mRNA) NM_014610 NM_008060
RefSeq (protein) NP_938148 NP_032086
Location (UCSC) Chr 11:
62.39 – 62.41 Mb
Chr 19:
8.9 – 8.92 Mb
PubMed search [1] [2]

Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene.[1][2][3]


Interactions[edit]

GANAB has been shown to interact with PTPRC.[4][5][6]

References[edit]

  1. ^ Treml K, Meimaroglou D, Hentges A, Bause E (May 2000). "The alpha- and beta-subunits are required for expression of catalytic activity in the hetero-dimeric glucosidase II complex from human liver". Glycobiology 10 (5): 493–502. doi:10.1093/glycob/10.5.493. PMID 10764838. 
  2. ^ Martiniuk F, Smith M, Ellenbogen A, Desnick RJ, Astrin K, Mitra J, Hirschhorn R (July 1983). "Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11". Cytogenet Cell Genet 35 (2): 110–6. doi:10.1159/000131851. PMID 6342981. 
  3. ^ "Entrez Gene: GANAB glucosidase, alpha; neutral AB". 
  4. ^ Arendt, C W; Ostergaard H L (May 1997). "Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II". J. Biol. Chem. (UNITED STATES) 272 (20): 13117–25. doi:10.1074/jbc.272.20.13117. ISSN 0021-9258. PMID 9148925. 
  5. ^ Baldwin, T A; Gogela-Spehar M; Ostergaard H L (October 2000). "Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction". J. Biol. Chem. (UNITED STATES) 275 (41): 32071–6. doi:10.1074/jbc.M003088200. ISSN 0021-9258. PMID 10921916. 
  6. ^ Baldwin, T A; Ostergaard H L (October 2001). "Developmentally regulated changes in glucosidase II association with, and carbohydrate content of, the protein tyrosine phosphatase CD45". J. Immunol. (United States) 167 (7): 3829–35. doi:10.4049/jimmunol.167.7.3829. ISSN 0022-1767. PMID 11564800. 

Further reading[edit]