GBLD-345

From Wikipedia, the free encyclopedia
Jump to: navigation, search
GBLD-345
GBLD-345 structure.png
Systematic (IUPAC) name
2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl] imidazo[2,1-f]pyridazin-6-amine
Clinical data
Legal status
?
Identifiers
ATC code ?
PubChem CID 4602899
Chemical data
Formula C21H21N5O2 
Mol. mass 375.423 g/mol
 YesY (what is this?)  (verify)

GBLD-345 is an anxiolytic drug used in scientific research, which acts as a non-selective, full-efficacy positive allosteric modulator of the GABAA receptor. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1]

References[edit]

  1. ^ Davies LP, Barlin GB, Ireland SJ, Ngu MM (October 1992). "Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors". Biochemical Pharmacology 44 (8): 1555–61. doi:10.1016/0006-2952(92)90472-U. PMID 1358075.