GCM1

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Glial cells missing homolog 1 (Drosophila)
Protein GCM1 PDB 1odh.png
PDB rendering based on 1odh.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols GCM1 ; GCMA; hGCMa
External IDs OMIM603715 MGI108045 HomoloGene2702 GeneCards: GCM1 Gene
RNA expression pattern
PBB GE GCM1 206269 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8521 14531
Ensembl ENSG00000137270 ENSMUSG00000023333
UniProt Q9NP62 P70348
RefSeq (mRNA) NM_003643 NM_008103
RefSeq (protein) NP_003634 NP_032129
Location (UCSC) Chr 6:
52.99 – 53.01 Mb
Chr 9:
78.05 – 78.07 Mb
PubMed search [1] [2]

Chorion-specific transcription factor GCMa is a protein that in humans is encoded by the GCM1 gene.[1][2]

This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.[2]

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