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Glial cells missing homolog 1 (Drosophila)
Protein GCM1 PDB 1odh.png
PDB rendering based on 1odh.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols GCM1 ; GCMA; hGCMa
External IDs OMIM603715 MGI108045 HomoloGene2702 GeneCards: GCM1 Gene
RNA expression pattern
PBB GE GCM1 206269 at tn.png
More reference expression data
Species Human Mouse
Entrez 8521 14531
Ensembl ENSG00000137270 ENSMUSG00000023333
UniProt Q9NP62 P70348
RefSeq (mRNA) NM_003643 NM_008103
RefSeq (protein) NP_003634 NP_032129
Location (UCSC) Chr 6:
52.99 – 53.01 Mb
Chr 9:
78.05 – 78.07 Mb
PubMed search [1] [2]

Chorion-specific transcription factor GCMa is a protein that in humans is encoded by the GCM1 gene.[1][2]

This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.[2]


Further reading[edit]