GDAP1

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Ganglioside induced differentiation associated protein 1
Identifiers
Symbols GDAP1 ; CMT4; CMT4A; CMTRIA
External IDs OMIM606598 MGI1338002 HomoloGene40713 GeneCards: GDAP1 Gene
RNA expression pattern
PBB GE GDAP1 221279 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 54332 14545
Ensembl ENSG00000104381 ENSMUSG00000025777
UniProt Q8TB36 O88741
RefSeq (mRNA) NM_001040875 NM_010267
RefSeq (protein) NP_001035808 NP_034397
Location (UCSC) Chr 8:
75.23 – 75.4 Mb
Chr 1:
17.15 – 17.16 Mb
PubMed search [1] [2]

Ganglioside-induced differentiation-associated protein 1 is a protein that in humans is encoded by the GDAP1 gene.[1][2]

This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms have been identified for this gene.[2]

References[edit]

  1. ^ Gauldie J, Bhandari SC, Singal DP (Apr 1976). "Alteration of the HL-A antigenic site in situ". Immunol Commun 4 (5): 465–76. doi:10.3109/08820137509057334. PMID 54332. 
  2. ^ a b "Entrez Gene: GDAP1 ganglioside-induced differentiation-associated protein 1". 

Further reading[edit]

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