GFRA3

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GDNF family receptor alpha 3
Protein GFRA3 PDB 2gh0.png
PDB rendering based on 2gh0.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols GFRA3 ; GDNFR3
External IDs OMIM605710 MGI1201403 HomoloGene1146 GeneCards: GFRA3 Gene
RNA expression pattern
PBB GE GFRA3 214479 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 2676 14587
Ensembl ENSG00000146013 ENSMUSG00000024366
UniProt O60609 O35118
RefSeq (mRNA) NM_001496 NM_010280
RefSeq (protein) NP_001487 NP_034410
Location (UCSC) Chr 5:
137.59 – 137.61 Mb
Chr 18:
34.69 – 34.72 Mb
PubMed search [1] [2]

GDNF family receptor alpha-3 (GFRα3), also known as the artemin receptor, is a protein that in humans is encoded by the GFRA3 gene.[1][2]

The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.[2]

See also[edit]

References[edit]

  1. ^ Jing S, Yu Y, Fang M, Hu Z, Holst PL, Boone T, Delaney J, Schultz H, Zhou R, Fox GM (Jan 1998). "GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family". J Biol Chem 272 (52): 33111–7. doi:10.1074/jbc.272.52.33111. PMID 9407096. 
  2. ^ a b "Entrez Gene: GFRA3 GDNF family receptor alpha 3". 

Further reading[edit]