GJA3

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Gap junction protein, alpha 3, 46kDa
Identifiers
Symbols GJA3 ; CTRCT14; CX46; CZP3
External IDs OMIM121015 MGI95714 HomoloGene9670 IUPHAR: Cx46 GeneCards: GJA3 Gene
RNA expression pattern
PBB GE GJA3 208590 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 2700 14611
Ensembl ENSG00000121743 ENSMUSG00000048582
UniProt Q9Y6H8 Q64448
RefSeq (mRNA) NM_021954 NM_001271623
RefSeq (protein) NP_068773 NP_001258552
Location (UCSC) Chr 13:
20.71 – 20.74 Mb
Chr 14:
57.04 – 57.06 Mb
PubMed search [1] [2]

Gap junction alpha-3 protein is a protein that in humans is encoded by the GJA3 gene.[1][2][3]

Interactions[edit]

GJA3 has been shown to interact with Tight junction protein 1.[4]

References[edit]

  1. ^ Mackay D, Ionides A, Kibar Z, Rouleau G, Berry V, Moore A, Shiels A, Bhattacharya S (May 1999). "Connexin46 mutations in autosomal dominant congenital cataract". Am J Hum Genet 64 (5): 1357–64. doi:10.1086/302383. PMC 1377871. PMID 10205266. 
  2. ^ Rosenberg AM, Gole GA (Jul 1982). "Morning Glory Syndrome: a report of two cases". Aust J Ophthalmol 9 (4): 263–5. doi:10.1111/j.1442-9071.1981.tb00919.x. PMID 7342922. 
  3. ^ "Entrez Gene: GJA3 gap junction protein, alpha 3, 46kDa". 
  4. ^ Nielsen, Peter A; Baruch Amos; Shestopalov Valery I; Giepmans Ben N G; Dunia Irene; Benedetti E Lucio; Kumar Nalin M (Jun 2003). "Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1)". Mol. Biol. Cell (United States) 14 (6): 2470–81. doi:10.1091/mbc.E02-10-0637. ISSN 1059-1524. PMC 194895. PMID 12808044. 

Further reading[edit]