GJB7

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Gap junction protein, beta 7, 25kDa
Identifiers
Symbols GJB7 ; CX25; bA136M9.1; connexin25
External IDs OMIM611921 HomoloGene89311 IUPHAR: Cx25 GeneCards: GJB7 Gene
Orthologs
Species Human Mouse
Entrez 375519 n/a
Ensembl ENSG00000164411 n/a
UniProt Q6PEY0 n/a
RefSeq (mRNA) NM_198568 n/a
RefSeq (protein) NP_940970 n/a
Location (UCSC) Chr 6:
87.99 – 88.04 Mb
n/a
PubMed search [1] n/a

Gap junction beta-7 protein (GJB7), also known as connexin-25 (Cx25), is a protein that in humans is encoded by the GJB7 gene.[1]

Function[edit]

Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[1][2]

References[edit]

  1. ^ a b "Entrez Gene: gap junction protein". 
  2. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.