GJC1

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Gap junction protein, gamma 1, 45kDa
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols GJC1 ; CX45; GJA7
External IDs OMIM608655 MGI95718 HomoloGene4016 IUPHAR: Cx45 GeneCards: GJC1 Gene
RNA expression pattern
PBB GE GJA7 208460 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10052 14615
Ensembl ENSG00000182963 ENSMUSG00000034520
UniProt P36383 P28229
RefSeq (mRNA) NM_001080383 NM_001159382
RefSeq (protein) NP_001073852 NP_001152854
Location (UCSC) Chr 17:
42.88 – 42.91 Mb
Chr 11:
102.8 – 102.82 Mb
PubMed search [1] [2]

Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) and connexin 45 (Cx45) — is a protein that in humans is encoded by the GJC1 gene.[1][2]

Function[edit]

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.[2]

References[edit]

  1. ^ Kanter HL, Saffitz JE, Beyer EC (Dec 1994). "Molecular cloning of two human cardiac gap junction proteins, connexin40 and connexin45". J Mol Cell Cardiol 26 (7): 861–8. doi:10.1006/jmcc.1994.1103. PMID 7966354. 
  2. ^ a b "Entrez Gene: GJA7 gap junction protein, alpha 7, 45kDa". 

Further reading[edit]

External links[edit]