GJD2

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Gap junction protein, delta 2, 36kDa
Identifiers
Symbols GJD2 ; CX36; GJA9
External IDs OMIM607058 MGI1334209 HomoloGene7734 IUPHAR: Cx36 GeneCards: GJD2 Gene
RNA expression pattern
PBB GE GJA9 221407 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 57369 14617
Ensembl ENSG00000159248 ENSMUSG00000068615
UniProt Q9UKL4 O54851
RefSeq (mRNA) NM_020660 NM_010290
RefSeq (protein) NP_065711 NP_034420
Location (UCSC) Chr 15:
35.04 – 35.05 Mb
Chr 2:
114.01 – 114.01 Mb
PubMed search [1] [2]

Gap junction delta-2 protein (GJD2) also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9) and is a protein that in humans is encoded by the GJD2 gene.[1][2]

Function[edit]

GJD2, also called connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. See GJB2 for additional background information on connexins.[2]

References[edit]

  1. ^ Belluardo N, Trovato-Salinaro A, Mudo G, Hurd YL, Condorelli DF (Oct 1999). "Structure, chromosomal localization, and brain expression of human Cx36 gene". J Neurosci Res 57 (5): 740–52. doi:10.1002/(SICI)1097-4547(19990901)57:5<740::AID-JNR16>3.0.CO;2-Z. PMID 10462698. 
  2. ^ a b "Entrez Gene: GJA9 gap junction protein, alpha 9, 36kDa". 

Further reading[edit]