GLG1

Golgi glycoprotein 1
Identifiers
Symbols	GLG1; CFR-1; DKFZp686L08213; ESL-1; FLJ23319; FLJ23967; FLJ32797; MG-160; MG160
External IDs	OMIM: 600753 MGI: 104967 HomoloGene: 7533 GeneCards: GLG1 Gene
Gene Ontology Molecular function • receptor binding Cellular component • Golgi membrane • Golgi apparatus • Golgi medial cisterna • membrane • integral to membrane • extracellular matrix Biological process • negative regulation of protein maturation by peptide bond cleavage • negative regulation of transforming growth factor beta receptor signaling pathway • regulation of chondrocyte differentiation • bone morphogenesis Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2734	20340
Ensembl	ENSG00000090863	ENSMUSG00000003316
UniProt	Q92896	Q3TMG0
RefSeq (mRNA)	NM_001145666.1	NM_009149.2
RefSeq (protein)	NP_001139138.1	NP_033175.1
Location (UCSC)	Chr 16: 74.48 – 74.64 Mb	Chr 8: 113.68 – 113.78 Mb
PubMed search	[1]	[2]

Golgi apparatus protein 1 is a protein that in humans is encoded by the GLG1 gene.

Further reading

• Burrus LW, Zuber ME, Lueddecke BA, Olwin BB (1992). "Identification of a cysteine-rich receptor for fibroblast growth factors". Mol. Cell. Biol. 12 (12): 5600–9. PMC 360499. PMID 1448090. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=360499. 
• Croul S, Mezitis SG, Stieber A, et al. (1990). "Immunocytochemical visualization of the Golgi apparatus in several species, including human, and tissues with an antiserum against MG-160, a sialoglycoprotein of rat Golgi apparatus". J. Histochem. Cytochem. 38 (7): 957–63. doi:10.1177/38.7.2355176. PMID 2355176. 
• Mourelatos Z, Gonatas JO, Cinato E, Gonatas NK (1997). "Cloning and sequence analysis of the human MG160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus". DNA Cell Biol. 15 (12): 1121–8. doi:10.1089/dna.1996.15.1121. PMID 8985126. 
• Steegmaier M, Borges E, Berger J, et al. (1997). "The E-selectin-ligand ESL-1 is located in the Golgi as well as on microvilli on the cell surface". J. Cell. Sci. 110 (6): 687–94. PMID 9099943. 
• Olofsson A, Hellman U, Ten Dijke P, et al. (1997). "Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160". Biochem. J. 324 (Pt 2): 427–34. PMC 1218448. PMID 9182700. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1218448. 
• Wild MK, Huang MC, Schulze-Horsel U, et al. (2001). "Affinity, kinetics, and thermodynamics of E-selectin binding to E-selectin ligand-1". J. Biol. Chem. 276 (34): 31602–12. doi:10.1074/jbc.M104844200. PMID 11404363. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Yamaguchi F, Morrison RS, Gonatas NK, et al. (2003). "Identification of MG-160, a FGF binding medial Golgi sialoglycoprotein, in brain tumors: an index of malignancy in astrocytomas". Int. J. Oncol. 22 (5): 1045–9. PMID 12684670. 
• Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. 
• Ahn J, Febbraio M, Silverstein RL (2005). "A novel isoform of human Golgi complex-localized glycoprotein-1 (also known as E-selectin ligand-1, MG-160 and cysteine-rich fibroblast growth factor receptor) targets differential subcellular localization". J. Cell. Sci. 118 (Pt 8): 1725–31. doi:10.1242/jcs.02310. PMID 15797922.