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Glycine receptor, alpha 3
Symbol GLRA3
External IDs OMIM600421 MGI95749 HomoloGene142 IUPHAR: 425 ChEMBL: 1075092 GeneCards: GLRA3 Gene
Species Human Mouse
Entrez 8001 110304
Ensembl ENSG00000145451 ENSMUSG00000038257
UniProt O75311 Q91XP5
RefSeq (mRNA) NM_001042543 NM_080438
RefSeq (protein) NP_001036008 NP_536686
Location (UCSC) Chr 4:
175.56 – 175.75 Mb
Chr 8:
55.94 – 56.13 Mb
PubMed search [1] [2]

The Glycine receptor subunit alpha-3 is a protein that in humans is encoded by the GLRA3 gene.[1] The protein encoded by this gene is a subunit of the glycine receptor.[1]

Variants of this receptor subunit is associated with susceptibility to epilepsy.[2]


  1. ^ a b Nikolic Z, Laube B, Weber RG, Lichter P, Kioschis P, Poustka A, Mulhardt C, Becker CM (Sep 1998). "The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts". J Biol Chem 273 (31): 19708–14. doi:10.1074/jbc.273.31.19708. PMID 9677400. 
  2. ^ Sobetzko D, Sander T, Becker CM (August 2001). "Genetic variation of the human glycine receptor subunit genes GLRA3 and GLRB and susceptibility to idiopathic generalized epilepsies". Am. J. Med. Genet. 105 (6): 534–8. doi:10.1002/ajmg.1488. PMID 11496371. 

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