GLRB

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"GLRB" is also the ICAO code for Roberts International Airport near Monrovia, Liberia.
Glycine receptor, beta
Protein GLRB PDB 1t3e.png
PDB rendering based on 1t3e.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols GLRB ; HKPX2
External IDs OMIM138492 MGI95751 HomoloGene20224 IUPHAR: β GeneCards: GLRB Gene
RNA expression pattern
PBB GE GLRB 205279 s at tn.png
PBB GE GLRB 205280 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 2743 14658
Ensembl ENSG00000109738 ENSMUSG00000028020
UniProt P48167 P48168
RefSeq (mRNA) NM_000824 NM_001281969
RefSeq (protein) NP_000815 NP_001268898
Location (UCSC) Chr 4:
158 – 158.09 Mb
Chr 3:
80.84 – 80.91 Mb
PubMed search [1] [2]

Glycine receptor subunit beta is a protein that in humans is encoded by the GLRB gene.[1][2][3]

The inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha (GLRA1, MIM 138491; GLRA2, MIM 305990) and beta subunits.[supplied by OMIM][3]

See also[edit]

References[edit]

  1. ^ Milani N, Mulhardt C, Weber RG, Lichter P, Kioschis P, Poustka A, Becker CM (Oct 1998). "The human glycine receptor beta subunit gene (GLRB): structure, refined chromosomal localization, and population polymorphism". Genomics 50 (3): 341–5. doi:10.1006/geno.1998.5324. PMID 9676428. 
  2. ^ Handford CA, Lynch JW, Baker E, Webb GC, Ford JH, Sutherland GR, Schofield PR (Oct 1996). "The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes". Brain Res Mol Brain Res 35 (1–2): 211–9. doi:10.1016/0169-328x(95)00218-h. PMID 8717357. 
  3. ^ a b "Entrez Gene: GLRB glycine receptor, beta". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.