GNG11

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Guanine nucleotide binding protein (G protein), gamma 11
Identifiers
Symbols GNG11 ; GNGT11
External IDs OMIM604390 MGI1913316 HomoloGene3045 GeneCards: GNG11 Gene
RNA expression pattern
PBB GE GNG11 204115 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 2791 66066
Ensembl ENSG00000127920 ENSMUSG00000032766
UniProt P61952 P61953
RefSeq (mRNA) NM_004126 NM_025331
RefSeq (protein) NP_004117 NP_079607
Location (UCSC) Chr 7:
93.55 – 93.56 Mb
Chr 6:
4 – 4.01 Mb
PubMed search [1] [2]

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 is a protein that in humans is encoded by the GNG11 gene.[1][2]

This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas.[2]

References[edit]

  1. ^ Ray K, Kunsch C, Bonner LM, Robishaw JD (Oct 1995). "Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits". J Biol Chem 270 (37): 21765–71. doi:10.1074/jbc.270.37.21765. PMID 7665596. 
  2. ^ a b "Entrez Gene: GNG11 guanine nucleotide binding protein (G protein), gamma 11". 

Further reading[edit]