GORASP2

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Golgi reassembly stacking protein 2, 55kDa
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols GORASP2 ; GOLPH6; GRASP55; GRS2; p59
External IDs OMIM608693 MGI2135962 HomoloGene9180 GeneCards: GORASP2 Gene
RNA expression pattern
PBB GE GORASP2 207812 s at tn.png
PBB GE GORASP2 208842 s at tn.png
PBB GE GORASP2 208843 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 26003 70231
Ensembl ENSG00000115806 ENSMUSG00000014959
UniProt Q9H8Y8 Q99JX3
RefSeq (mRNA) NM_001201428 NM_027352
RefSeq (protein) NP_001188357 NP_081628
Location (UCSC) Chr 2:
171.78 – 171.82 Mb
Chr 2:
70.66 – 70.71 Mb
PubMed search [1] [2]

Golgi reassembly-stacking protein 2 is a protein that in humans is encoded by the GORASP2 gene.[1][2]

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in establishing the stacked structure of the Golgi apparatus.[2]

Interactions[edit]

GORASP2 has been shown to interact with BLZF1,[3] TGF alpha,[3] TMED2[3] and GOLGA2.[1][3][4]

References[edit]

  1. ^ a b Shorter J, Watson R, Giannakou ME, Clarke M, Warren G, Barr FA (Nov 1999). "GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system". EMBO J 18 (18): 4949–60. doi:10.1093/emboj/18.18.4949. PMC 1171566. PMID 10487747. 
  2. ^ a b "Entrez Gene: GORASP2 golgi reassembly stacking protein 2, 55kDa". 
  3. ^ a b c d Barr, F A; Preisinger C; Kopajtich R; Körner R (Dec 2001). "Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus". J. Cell Biol. (United States) 155 (6): 885–91. doi:10.1083/jcb.200108102. ISSN 0021-9525. PMC 2150891. PMID 11739402. 
  4. ^ Short, B; Preisinger C; Körner R; Kopajtich R; Byron O; Barr F A (Dec 2001). "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic". J. Cell Biol. (United States) 155 (6): 877–83. doi:10.1083/jcb.200108079. ISSN 0021-9525. PMC 2150909. PMID 11739401. 

Further reading[edit]