GPR128

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G protein-coupled receptor 128
Identifiers
Symbols GPR128 ; FLJ14454; FLJ16382; FLJ29035; MGC142011; MGC163260
External IDs OMIM612307 MGI2441732 HomoloGene13115 IUPHAR: GPR128 GeneCards: GPR128 Gene
RNA expression pattern
PBB GE GPR128 gnf1h00942 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 84873 239853
Ensembl ENSG00000144820 ENSMUSG00000022755
UniProt Q96K78 Q8BM96
RefSeq (mRNA) NM_032787 NM_172825
RefSeq (protein) NP_116176 NP_766413
Location (UCSC) Chr 3:
100.33 – 100.41 Mb
Chr 16:
56.72 – 56.8 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 128 is a protein that in humans is encoded by the GPR128 gene.[1][2] It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.[3][4]

References[edit]

  1. ^ "Entrez Gene: GPR128 G protein-coupled receptor 128". 
  2. ^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. 
  3. ^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 1-4419-7912-3. 
  4. ^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914. 

Further reading[edit]