GPR17

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G protein-coupled receptor 17
Identifiers
Symbols GPR17 ; DKFZp686M18273
External IDs OMIM603071 MGI3584514 HomoloGene83191 IUPHAR: GPR17 ChEMBL: 1075162 GeneCards: GPR17 Gene
RNA expression pattern
PBB GE GPR17 206190 at tn.png
PBB GE GPR17 215225 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 2840 574402
Ensembl ENSG00000144230 ENSMUSG00000052229
UniProt Q13304 Q6NS65
RefSeq (mRNA) NM_001161415 NM_001025381
RefSeq (protein) NP_001154887 NP_001020552
Location (UCSC) Chr 2:
128.4 – 128.41 Mb
Chr 18:
31.94 – 31.95 Mb
PubMed search [1] [2]

Uracil nucleotide/cysteinyl leukotriene receptor is a protein that in humans is encoded by the GPR17 gene.[1][2] This gene has been found to regulate food intake response mediated by FOXO1.[3]


References[edit]

  1. ^ Raport CJ, Schweickart VL, Chantry D, Eddy RL Jr, Shows TB, Godiska R, Gray PW (Feb 1996). "New members of the chemokine receptor gene family". J Leukoc Biol 59 (1): 18–23. PMID 8558062. 
  2. ^ "Entrez Gene: GPR17 G protein-coupled receptor 17". 
  3. ^ Ren, Hongxia; Orozco, Ian J.; Su, Ya; Suyama, Shigetomo; Gutiérrez-Juárez, Roger; Horvath, Tamas L.; Wardlaw, Sharon L.; Plum, Leona; Arancio, Ottavio; Accili, Domenico. "FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake". Cell 149 (6): 1314–1326. doi:10.1016/j.cell.2012.04.032. 

Further reading[edit]