GPR179

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G protein-coupled receptor 179
Identifiers
Symbols GPR179 ; CSNB1E; GPR158L; GPR158L1
External IDs OMIM614515 MGI2443409 HomoloGene34917 IUPHAR: GPR179 GeneCards: GPR179 Gene
Orthologs
Species Human Mouse
Entrez 440435 217143
Ensembl ENSG00000188888 ENSMUSG00000070337
UniProt Q6PRD1 E9PY61
RefSeq (mRNA) NM_001004334 NM_001081220
RefSeq (protein) NP_001004334 NP_001074689
Location (UCSC) Chr 17:
36.48 – 36.5 Mb
Chr 11:
97.33 – 97.35 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 179 is a protein that in humans is encoded by the GPR179 gene.[1]

Clinical relevance[edit]

Mutations in this gene have been associated to cases of congenital stationary Night Blindness.[2]

References[edit]

  1. ^ "Entrez Gene: GPR179 G protein-coupled receptor 179". 
  2. ^ Audo I, Bujakowska K, Orhan E, Poloschek CM, Defoort-Dhellemmes S, Drumare I, Kohl S, Luu TD, Lecompte O, Zrenner E, Lancelot ME, Antonio A, Germain A, Michiels C, Audier C, Letexier M, Saraiva JP, Leroy BP, Munier FL, Mohand-Saïd S, Lorenz B, Friedburg C, Preising M, Kellner U, Renner AB, Moskova-Doumanova V, Berger W, Wissinger B, Hamel CP, Schorderet DF, De Baere E, Sharon D, Banin E, Jacobson SG, Bonneau D, Zanlonghi X, Le Meur G, Casteels I, Koenekoop R, Long VW, Meire F, Prescott K, de Ravel T, Simmons I, Nguyen H, Dollfus H, Poch O, Léveillard T, Nguyen-Ba-Charvet K, Sahel JA, Bhattacharya SS, Zeitz C (Feb 10, 2012). "Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness.". American Journal of Human Genetics 90 (2): 321–30. doi:10.1016/j.ajhg.2011.12.007. PMC 3276675. PMID 22325361. 

Further reading[edit]

  • Bjarnadóttir TK, Fredriksson R, Schiöth HB (2006). "The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors.". Gene 362: 70–84. doi:10.1016/j.gene.2005.07.029. PMID 16229975.