N-arachidonyl glycine receptor also known as G-protein coupled receptor 18 (GPR18) is a protein that in humans is encoded by the GPR18gene. Along with the other previously "orphan" receptors GPR55 and GPR119, GPR18 has been found to be a receptor for endogenous lipid neurotransmitters, several of which also bind to cannabinoid receptors.
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^Kohno M, et al. (September 2006). "Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18". Biochem. Biophys. Res. Commun.347 (3): 827–32. doi:10.1016/j.bbrc.2006.06.175. PMID16844083.
^Lu, VB; Puhl HL, 3rd; Ikeda, SR (Jan 2013). "N-Arachidonyl glycine does not activate G protein-coupled receptor 18 signaling via canonical pathways.". Molecular pharmacology83 (1): 267–82. PMID23104136.Cite uses deprecated parameters (help)
^McHugh D, Page J, Dunn E, Bradshaw HB (May 2011). "Δ(9) -THC and N-arachidonyl glycine are full agonists at GPR18 and cause migration in the human endometrial cell line, HEC-1B". Br J Pharmacol165 (8): no. doi:10.1111/j.1476-5381.2011.01497.x. PMID21595653.
Christian SL, et al. (2002). "An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia". Genomics79 (5): 635–56. doi:10.1006/geno.2002.6765. PMID11991713.
Kohno M, et al. (2006). "Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18". Biochem. Biophys. Res. Commun.347 (3): 827–32. doi:10.1016/j.bbrc.2006.06.175. PMID16844083.