Probable G-protein coupled receptor 34 is a protein that in humans is encoded by the GPR34gene.
G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM]
Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res.6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID8889549.
Jacobi FK, Broghammer M, Pesch K, et al. (2000). "Physical mapping and exclusion of GPR34 as the causative gene for congenital stationary night blindness type 1". Hum. Genet.107 (1): 89–91. doi:10.1007/s004390050017. PMID10982042.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res.12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID16303743.
Engemaier E, Römpler H, Schöneberg T, Schulz A (2006). "Genomic and supragenomic structure of the nucleotide-like G-protein-coupled receptor GPR34". Genomics87 (2): 254–64. doi:10.1016/j.ygeno.2005.10.001. PMID16338117.