Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45gene.
This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.
Kawasawa Y, Kume K, Nakade S et al. (2000). "Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45". Biochem. Biophys. Res. Commun.276 (3): 952–6. doi:10.1006/bbrc.2000.3569. PMID11027574.CS1 maint: Explicit use of et al. (link)
Kawasawa Y, Kume K, Izumi T, Shimizu T (2000). "Mammalian PSP24s (alpha and beta isoforms) are not responsive to lysophosphatidic acid in mammalian expression systems". Biochem. Biophys. Res. Commun.276 (3): 957–64. doi:10.1006/bbrc.2000.3570. PMID11027575.
Hillier LW, Graves TA, Fulton RS et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature434 (7034): 724–31. doi:10.1038/nature03466. PMID15815621.CS1 maint: Explicit use of et al. (link)