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G protein-coupled receptor 45
Symbols GPR45 ; PSP24; PSP24(ALPHA); PSP24A
External IDs OMIM604838 MGI2135882 HomoloGene5228 IUPHAR: 106 GeneCards: GPR45 Gene
RNA expression pattern
PBB GE GPR45 211175 at tn.png
More reference expression data
Species Human Mouse
Entrez 11250 93690
Ensembl ENSG00000135973 ENSMUSG00000041907
UniProt Q9Y5Y3 Q9EQQ4
RefSeq (mRNA) NM_007227 NM_053107
RefSeq (protein) NP_009158 NP_444337
Location (UCSC) Chr 2:
105.24 – 105.24 Mb
Chr 1:
42.95 – 43.04 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.[1][2]

This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.[2]


  1. ^ Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF (May 1999). "Discovery of three novel orphan G-protein-coupled receptors". Genomics 56 (1): 12–21. doi:10.1006/geno.1998.5655. PMID 10036181. 
  2. ^ a b "Entrez Gene: GPR45 G protein-coupled receptor 45". 

Further reading[edit]