From Wikipedia, the free encyclopedia
Jump to: navigation, search
G protein-coupled receptor, family C, group 5, member C
Symbols GPRC5C ; RAIG-3; RAIG3
External IDs OMIM605949 MGI1917605 HomoloGene11099 IUPHAR: GPRC5C GeneCards: GPRC5C Gene
RNA expression pattern
PBB GE GPRC5C 219327 s at tn.png
More reference expression data
Species Human Mouse
Entrez 55890 70355
Ensembl ENSG00000170412 ENSMUSG00000051043
UniProt Q9NQ84 Q8K3J9
RefSeq (mRNA) NM_018653 NM_001110337
RefSeq (protein) NP_061123 NP_001103807
Location (UCSC) Chr 17:
72.42 – 72.45 Mb
Chr 11:
114.85 – 114.87 Mb
PubMed search [1] [2]

G-protein coupled receptor family C group 5 member C is a protein that in humans is encoded by the GPRC5C gene.[1][2]

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.[2]

See also[edit]


  1. ^ Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN (Nov 2000). "Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C)". Genomics 67 (1): 8–18. doi:10.1006/geno.2000.6226. PMID 10945465. 
  2. ^ a b "Entrez Gene: GPRC5C G protein-coupled receptor, family C, group 5, member C". 

External links[edit]

  • "GPRC5 Receptors: RAIG3". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.