GRIP1 (gene)

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Glutamate receptor interacting protein 1
Protein GRIP1 PDB 1m5z.png
PDB rendering based on 1m5z.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols GRIP1 ; GRIP
External IDs OMIM604597 MGI1921303 HomoloGene12938 GeneCards: GRIP1 Gene
RNA expression pattern
PBB GE GRIP1 214018 at tn.png
More reference expression data
Species Human Mouse
Entrez 23426 74053
Ensembl ENSG00000155974 ENSMUSG00000034813
UniProt Q9Y3R0 Q925T6
RefSeq (mRNA) NM_001178074 NM_001277292
RefSeq (protein) NP_001171545 NP_001264221
Location (UCSC) Chr 12:
66.74 – 67.2 Mb
Chr 10:
119.45 – 120.09 Mb
PubMed search [1] [2]

Glutamate receptor-interacting protein 1 is a protein that in humans is encoded by the GRIP1 gene.[1][2]


GRIP1 (gene) has been shown to interact with:


  1. ^ Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (April 1999). "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains". Neuron 22 (3): 511–24. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531. 
  2. ^ "Entrez Gene: GRIP1 glutamate receptor interacting protein 1". 
  3. ^ a b c d e Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK (May 2002). "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs". J. Biol. Chem. 277 (18): 15221–4. doi:10.1074/jbc.C200112200. PMID 11891216. 
  4. ^ Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM, Couthino V (February 2003). "Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP". Neuron 37 (4): 625–38. doi:10.1016/S0896-6273(02)01191-1. PMC 3314502. PMID 12597860. 
  5. ^ Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (June 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157. 

Further reading[edit]