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GTP binding protein 1
Symbols GTPBP1 ; GP-1; GP1; HSPC018
External IDs OMIM602245 MGI109443 HomoloGene3165 GeneCards: GTPBP1 Gene
RNA expression pattern
PBB GE GTPBP1 219357 at tn.png
More reference expression data
Species Human Mouse
Entrez 9567 14904
Ensembl ENSG00000100226 ENSMUSG00000042535
UniProt O00178 O08582
RefSeq (mRNA) NM_004286 NM_013818
RefSeq (protein) NP_004277 NP_038846
Location (UCSC) Chr 22:
39.1 – 39.13 Mb
Chr 15:
79.69 – 79.72 Mb
PubMed search [1] [2]

GTP-binding protein 1 is a protein that in humans is encoded by the GTPBP1 gene.[1][2]

This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mice, where disruption of the gene for that protein had no observable phenotype.[2]


  1. ^ Senju S, Nishimura Y (Apr 1997). "Identification of human and mouse GP-1, a putative member of a novel G-protein family". Biochem Biophys Res Commun 231 (2): 360–4. doi:10.1006/bbrc.1997.6103. PMID 9070279. 
  2. ^ a b "Entrez Gene: GTPBP1 GTP binding protein 1". 

Further reading[edit]