Born in Turin, Piedmont, Italy to a Venetian father and Sicilian mother, Garko was raised in the nearby suburb of Settimo Torinese. His film credits include Callas Forever (2002) and L'Onore and il Rispetto (2006) a television mini-series where he portrayed a ruthless fictitious Mafia boss "Tonio Fortebracci". He starred alongside actresses Serena Autieri and Manuela Arcuri. In 2010 he had the main role of "Nito Valdi" in another mini-series Il peccato e la vergogna, which was set in Italy during World War II. Manuela Arcuri was his co-star in this series as well. In 2011, he starred in the television mini-series Viso d'angelo (Angel Face), a police thriller.