Gallamine triethiodide
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(Redirected from Gallamine)
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| Systematic (IUPAC) name | |
| 2,2’,2’’-[benzene-1,2,3-triyltris(oxy)]tris(N,N,N-triethylethanaminium) triiodide | |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 65-29-2  |
| ATC code | M03AC02 |
| PubChem | CID 6172 |
| IUPHAR ligand | 356 |
| DrugBank | DB00483 |
| ChemSpider | 5937  |
| UNII | Q3254X40X2 |
| KEGG | D02292 |
| ChEBI | CHEBI:503442 |
| ChEMBL | CHEMBL1200993 |
| Chemical data | |
| Formula | C30H60N3O3+3 · 3 I- (gallamine triethiodide) C24H45N3O3 (gallamine) |
| Mol. mass | 891.529 g/mol (gallamine triethiodide) 423.633 g/mol (gallamine) |
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Gallamine triethiodide (Flaxedil) is a non-depolarising muscle relaxant.[1] It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine.[2] Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release.
Gallamine triethiodide is commonly used to stabilize muscle contractions during surgical procedures.
It was developed by Daniel Bovet in 1947.[3]
References [edit]
- ^ "Webster's Online Dictionary - Flaxedil". Retrieved 2008-12-15.
- ^ "RxMed: Pharmaceutical Information - FLAXEDIL". Retrieved 2008-12-15.
- ^ Raghavendra T (July 2002). "Neuromuscular blocking drugs: discovery and development". J R Soc Med 95 (7): 363–7. doi:10.1258/jrsm.95.7.363. PMC 1279945. PMID 12091515.
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