The Gayaza-Ziroobwe Road starts at Gayaza and goes through Namulonge, Busiika and ends in Ziroobwe, a distance of 28 kilometres (17 mi). The coordinates of the road near Busiika in Luweero District are Coordinates: .
Prior to 2007, the road had a gravel surface. In 2008, the Uganda Government began to upgrade the road from gravel to bitumen at an estimated cost of US$40 million. The work, undertaken by a Serbian firm, Energoprojekt, commenced in March 2007 and was originally expected to be completed in November 2009. The construction and improvement of the road has been extended to include the Kampala-Gayaza section of the road. Due to repeated delays, the completion date has now been set for June 2011.
The following landmarks lie close or near the Gayaza-Ziroobwe Road:
- The town of Gayaza in Wakiso District, 3 kilometres (1.9 mi), by road, east of Kasangati
- Gayaza High School - A prestigious all girls boarding high school established in 1905
- Kabanyolo Farm - An agricultural and livestock farm that belongs to the Faculty of Agriculture and Faculty of Veterinary Medicine, at Makerere University.
- The town of Namulonge in Wakiso District
- The main campus of Bugema University at Bugema in Luweero District
- The town of Busiika in Luweero District
- The town of Ziroobwe in Luweero District
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